| CA125和CA199检测对卵巢上皮癌的诊断价值 |
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| 引用本文： | 丁永慧,张治宁. CA125和CA199检测对卵巢上皮癌的诊断价值[J]. 宁夏医科大学学报, 2005, 27(6): 454-456 |
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| 作者姓名： | 丁永慧 张治宁 |
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| 作者单位： | 宁夏医学院附属医院妇产科,银川,750004;宁夏医学院附属医院妇产科,银川,750004 |
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| 摘 要： | 目的探讨血清CA125和CA199检测对卵巢上皮癌的临床价值.方法卵巢上皮癌患者68例及卵巢上皮类良性肿瘤患者32例术前进行血清CA125、CA199测定;卵巢上皮癌患者每次化疗前复查血清CA125、CA199,以CA125和CA199检测任何一项阳性视为联合检测阳性统计.结果CA125检测的敏感度为77.9%,特异度为93.8%;CA199检测的敏感度为41.2%,特异度为96.9%;联合检测敏感度为92.6%,特异度为90.6%;血清CA125对卵巢浆液性囊腺癌和粘液性囊腺癌的灵敏度分别为93.8%和36.8%;CA199为24.5%和84.2%;Ⅲ Ⅳ期卵巢上皮癌患者的CA125和CA199明显高于Ⅰ Ⅱ期患者;术后血清CA125、CA199值未降至正常或降至正常后又升高者预后不良或复发.结论血清CA125和CA199是卵巢上皮癌诊断和判断预后的敏感性指标,CA125对卵巢浆液性癌较敏感,CA199对卵巢粘液性癌较敏感,二者联合检测可提高诊断的敏感性和特异度.
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| 关 键 词： | CA125 CA199 卵巢上皮癌 |
| 文章编号： | 1005-8486(2005)06-0454-03 |
| 修稿时间： | 2005-09-05 |
The Value Analysis of Serum CA125 and CA199 in Ovarian Cancer |
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| DING Yong-hui,ZHANG Zhi-ning. The Value Analysis of Serum CA125 and CA199 in Ovarian Cancer[J]. Journal of Ningxia Medical College, 2005, 27(6): 454-456 |
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| Authors: | DING Yong-hui ZHANG Zhi-ning |
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| Abstract: | |
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| Keywords: | CA125 CA199 |
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