心脉舒胶囊制备工艺的优选研究

目的:优选心脉舒胶囊最佳制备工艺.方法:以芍药苷提取率和干浸膏得率为考察指标,应用正交试验设计筛选心脉舒胶囊最佳制备工艺条件.结果:处方药材加水煎煮提取2次:第一次加10倍量水,煎煮1.5小时;第二次加8倍量水,煎煮1.5小时,提取液滤过,合并,浓缩至1.0g生药/ml,加95%乙醇调节含醇量至80%,充分搅拌,静置12小时.结论:优选的最佳制备工艺稳定可行.

Optimum Selection of the Preparation Procedure of Xinmaishu Capsule

Objective:To choose the preparation procedure of Xinmaishu capsule.Methods:The optimal preparation process was selected with the orthogonal design.The extraction percentage of peoniflorin and the yield of extracts were used to evaluate the factor levels.Results:The optimal preparation process was:extracted with water for 2 times,first 10 times amount,extracted 1.5h,then 8 times amount,extracted 1.5h.The optimal procedure of ethanol precipitation was 1.0g/ml, 80% ethanol,laying up 12 hours.Conlusions:This preparation condition is the best way.