| Protective Effects of Calcium Antagonists on Cadmium—induced Toxicity in Rats |
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| 引用本文： | YANGXIAO－FANG YANGYONG－NＩＡＮ.Protective Effects of Calcium Antagonists on Cadmium—induced Toxicity in Rats[J].生物医学与环境科学,1997,10(4):402-407. |
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| 作者姓名： | YANGXIAO－FANG YANGYONG－NＩＡＮ |
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| 作者单位： | [1]InstituteofAppliedToxicology,NanjingMedicalUniersity,Nanjing210029 [2]InstituteofAppliedToxicology,Nanji |
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| 摘 要： | INTRODUCTIONCadmium,oneoftheimPOrtantenvironmentalpollutants,isknowntocausere-nal,hepatic,neurologicandtesticulardisorders.ThemechanismofheavymetaItoxi-cityremainsunclearalthoughmuchresearchhasbeendonesincethe192Os.Anditwasreportedthatthemetalchelatorsusedinthetherapyofsuchheavymeta1induceddiseasesmaycausesideeffectsonthepatients(Knandelwaletal.,l987).Recently,anewhypothesissuggestedthatcalmodulin(CaM),theuniquemodulatorproteinofcalciumdependentfunctions,mightbethefirsttargetmoleculefo…
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| 关 键 词： | 钙离子阻断剂 钙中毒 大鼠 作用机制 |
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