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Silicon carbide: a versatile material for biosensor applications
Authors:Alexandra Oliveros  Anthony Guiseppi-Elie  Stephen E Saddow
Institution:1. Department of Electrical Engineering, University of South Florida, 4202 East Fowler Avenue, Tampa, FL, 33620-5350, USA
2. Center for Bioelectronics, Biosensors and Biochips (C3B), Clemson University Advanced Materials Center, 100 Technology Drive, Anderson, SC, 29625, USA
3. Department of Electrical and Computer Engineering, Clemson University, 132 Earle Hall, Clemson, SC, 29634, USA
4. Department of Molecular Pharmacology and Physiology, University of South Florida, 4202 E. Fowler Ave, Tampa, FL, 33620, USA
Abstract:Silicon carbide (SiC) has been around for more than 100 years as an industrial material and has found wide and varied applications because of its unique electrical and thermal properties. In recent years there has been increased attention to SiC as a viable material for biomedical applications. Of particular interest in this review is its potential for application as a biotransducer in biosensors. Among these applications are those where SiC is used as a substrate material, taking advantage of its surface chemical, tribological and electrical properties. In addition, its potential for integration as system on a chip and those applications where SiC is used as an active material make it a suitable substrate for micro-device fabrication. This review highlights the critical properties of SiC for application as a biosensor and reviews recent work reported on using SiC as an active or passive material in biotransducers and biosensors.
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