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抗肿瘤金属配合物药物及其药理作用的研究进展
引用本文:牟永平,吴刚,周立社,和彦苓. 抗肿瘤金属配合物药物及其药理作用的研究进展[J]. 中国药理学通报, 2007, 23(11): 1409-1413
作者姓名:牟永平  吴刚  周立社  和彦苓
作者单位:1. 包头医学院,生物化学与分子生物学教研室,内蒙古,包头,014010
2. 包头医学院,生物化学与分子生物学教研室,内蒙古,包头,014010;包头医学院,生物医学研究中心,内蒙古,包头,014010;包头医学院,生物微量元素研究所,内蒙古,包头,014010
3. 包头医学院,生物医学研究中心,内蒙古,包头,014010
4. 包头医学院,生物微量元素研究所,内蒙古,包头,014010
摘    要:自从顺铂作为抗肿瘤药物被开发利用以来,无机金属配合物药物已成为新的一类抗癌化疗药物。该文参阅国内外相关文献,介绍抗肿瘤铂及其它金属配合物药物的抗肿瘤机制及其药理作用,对抗肿瘤金属配合物药物的研究进展进行综述。

关 键 词:抗肿瘤  金属  配合物
文章编号:1001-1978(2007)11-1409-05
修稿时间:2007-06-20

Research progress in anticancer drugs of the metallic complexes and their pharmacological effect
MU Yong-ping,WU Gang,ZHOU Li-she,HE Yan-ling. Research progress in anticancer drugs of the metallic complexes and their pharmacological effect[J]. Chinese Pharmacological Bulletin, 2007, 23(11): 1409-1413
Authors:MU Yong-ping  WU Gang  ZHOU Li-she  HE Yan-ling
Affiliation:1. Dept of Biochemistry and Molecular Biology ;2. The Research Center of Biology and Medicine; 3. The Research Institute of Trace Element in Organism, Baotou Medical College, Baotou Neimenggu 014010, China
Abstract:The inorganic drug of the metal complexes has been a new anticancer drug of chemical therapy, since cisplatin was used in clinic as an anticancer drug . This review introduced the mechanism of anticancer action of the anticancer drugs of platinum and other metallic complexes and their pharmacological effect, and the research progress in anticancer drugs of the metallic complexes were reviewed in this article.
Keywords:anticancer   metal    complexes
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