| 阿昔洛韦眼用凝胶体外释药研究 |
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| 引用本文： | 卢荣枝,唐干益. 阿昔洛韦眼用凝胶体外释药研究[J]. 中国药房, 2005, 16(8): 583-584 |
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| 作者姓名： | 卢荣枝 唐干益 |
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| 作者单位： | 1. 广东省中山市人民医院药剂科,中山市,528403
2. 深圳市流花医院药剂科,深圳市,518005 |
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| 摘 要： | 目的:研究阿昔洛韦眼用凝胶的体外释放特性。方法:以磷酸盐缓冲液为释放介质,以高效液相色谱法测定释放介质中阿昔洛韦的含量,用透析袋法研究阿昔洛韦眼用凝胶中药物的释放特性。结果:阿昔洛韦眼用凝胶体外释放曲线符合一级释药方程。结论:阿昔洛韦眼用凝胶具有一定的缓释特性。
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| 关 键 词： | 阿昔洛韦 体外释药 高效液相色谱法 透析袋法 |
| 文章编号： | 1001-0408(2005)08-0583-02 |
| 修稿时间： | 2004-09-21 |
Study on the Drug-releasing of Aciclovir Eye Gel in Vitro |
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| LU Rongzhi,TANG Ganyi. Study on the Drug-releasing of Aciclovir Eye Gel in Vitro[J]. China Pharmacy, 2005, 16(8): 583-584 |
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| Authors: | LU Rongzhi TANG Ganyi |
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| Abstract: | OBJECTIVE:To study the drug-releasing characteristics of acyclovir eye gel in vitro.METHODS:The buffer phosphate was taken as the releasing mediator,the content of the aciclovir in the releasing mediator was determined by HPLC,the drug releasing charactersitic of aciclovir eye gel was studied by bag filter method.RESULTS:The releasing curve of the aciclovir eye gel in vitro was in line with the first-order drug releasing equation.CONCLUSION:The aciclovir eye gel is characterized by slow-release to some degree. |
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| Keywords: | Aciclovir Drug-releasing in vitro HPLC Bag filter method |
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