浅谈有关“体质-亚健康-病证”演变关系轴的中西医结合研究思路

为了探索从健康到亚健康，再到疾病发展过程中所遵循的客观规律及关键因素，我们提出了“体质－亚健康－病证”演变关系轴的研究思路。这种演变关系轴以中医体质学说为轴心，以亚健康状态下反应疾病量变积累的相关生理病理性指标为坐标，同时探寻并逐步阐明促进发病及导致质变的关键因素。研究方向主要从横纵两个方向入手，通过对比体质相同的人群在健康、亚健康、疾病3种不同的状态下生理病理情况进行横向研究，结合同一个人在3种不同状态的纵向研究，并通过不同类型的体质的分项研究总结到总体研究，再把总体的研究成果分别应用到不同体质的分类当中，从探索疾病从无到有发展过程中所具有的共性。

Integrative Medical Research Thinking on the Constitution-Subhealth-Disease Relation Developing Axis

In order to explore the objective rule and the key factors in the development of diseases,the process from quantitative change to qualitative change,and from health through sub-health to disease,a new thinking of research,enitled by ＂Constitution-Subhealth-Disease Relation Developing Axis＂ is offered by the author.This axis took the CM theory on body constitution as a core,with the coordinates composed of physiological and pathological indices concerning the quantitative changes of illness accumulated under sub-health state.Meanwhile,the key factors for advancing the access and inducing qualitative change of illness were denoted.The orientation of the research is starting from two aspects,horizontally on the crowd possessing the same body constitution,and longitudinally on the same person in different conditions.The research sum-up the general rule of disease occurrence through individually studying the process in persons with different body constitutions,then the commonness of diseases developed from the bottom was explored by applying the outcomes of the foregoing global study on the sorted researches of different constitutions.