基于脑电的多模态神经功能成像新技术研究进展

神经功能成像能够实现活体脑结构与功能变化的无创(微创)检测。鉴于头皮脑电具有高时间分辨、便于操作、能直接反映大脑神经生理活动等优点,近年已逐步整合形成脑电-功能磁共振成像(EEG-fMRI)、脑电-近红外光谱(EEG-NIRS)、脑电-经颅聚焦超声(EEG-tFUS)等兼具高时空分辨优势的多模态神经功能成像新技术。从技术原理、技术特征及其在神经功能研究中的最新进展等方面,综述3种新模式的研究现状,论述存在问题与发展趋势,突出多模态神经功能成像新技术在促进脑科学发展中的意义。

Research Progress of Multimodal Functional Neural ImagingTechnology Based on EEG

Functional neural imaging is able to non-invasively detect the changes in structure and function of living brain. The scalp electroencephalogram has the advantages of high time resolution,easy operation and direct reflection of the brain's neurophysiological activities. It has been integrated into the new multimodal functional neural imaging technology with both high temporal and spatial resolution. In this paper,electroencephalogram functional magnetic resonance imaging (EEG-fMRI),electroencephaloelectric near-infrared spectroscopy (EEG-NIRS) and brain electric transcranial focused ultrasound (EEG-tFUS) were taken as examples to reflect the current state of the development. The main contents included technical principles,technical characteristics and the latest progress in neural function research. In addition,the shortcomings and development trend of the three new models were discussed in detail to promote the research and application of multimodal functional neural imaging technology in brain science.