60例糖尿病前期患者综合干预管理效果观察

目的]分析对糖尿病前期患者进行综合干预管理的效果。方法]对某大型企业在职职工1 817人,使用葡萄糖氧化酶法检测空腹和餐后2 h静脉血浆血糖。对检出的60例糖尿病前期患者进行综合干预管理2年。结果]干预管理后糖尿病知识知晓率、血压控制率、经常锻炼率较干预前有明显提高,差异有统计学意义,空腹血糖较干预前下降。60例中有14例发生糖尿病,其中单纯空腹血糖受损(IFG)年转变率为3.8%,单纯糖耐量减低(IGT)为10.5%,空腹血糖受损兼有糖耐量减低(IFG/IGT)为27.8%。IFG与IGT糖尿病年转变率差异无统计学意义;IFG/IGT糖尿病年转变率高于IFG,差异有统计学意义;IGT与IFG/IGT糖尿病年转变率差异无统计学意义。结论]对IFG、IGT及IFG/IGT者均应给予积极的干预,特别是对IFG/IGT者,从而降低糖尿病的发病率。

Observation on the effect of comprehensive intervention for 60 cases of prediabetes

Objective] To investigate the incidence of diabetes mellitus(DM) in prediabetes and the effect of comprehensive intervention and management on these prediabetic patients. Methods] Patients with impaired fasting glucose(IFG) and impaired glucose tolerance levels(IGT) were screened out by glucokinase method and oral glucose tolerance test among 1 817 workers in a lage enterprise.They were follwed up for 2 years with comprehensive intervention. Results] Compared with their baseline levels,the awareness rate of DM,controlled rate of hypertension and rate of often exercising increased significantly.Their levels of fasting blood glucose had dropped.Of the 60 prediabetes 14 turned to be diabetes.Among them the annual conversion rates were 3.8%,10.5%and 27.8% for the subjects with IFG,IGT and IFG/IGT respectively.The conversion rate was significantly higher among IFG/IGT than that of IFG. Conclusion] Active intervention should be done on the prediabetes,especially on the IFG/IGT subjects to reduce the incidence of DM.