血脂异常与冠状动脉病变程度的相关性分析

目的：探讨冠状动脉病变与血脂异常的关系。方法：将100例疑似冠心病的患者依据冠状动脉造影结果分为：正常组；1支病变组；2支病变组；3支病变组。同时测定并统计分析血脂各成分与冠状动脉病变之问的关系。结果：各组的总胆同醇（TC）、甘油三酯（TG）差异无显著性。1支病变组，2支病变组在低密度脂蛋白（LDL-C）水平上与正常组比较未见明显增高。但在高密度脂蛋白（HDL-C）水平上，与正常组比较有明显降低且有统计学意义。3支病变组与正常组比较。低密度脂蛋白（LDL-C）明显增高，高密度脂蛋白（HDL-C）明显降低且有统计学意义。结论：血脂各成分与冠状动脉病变相关性分析表明：LDL-C增高和HDL-C降低与冠状动脉病变相关，其中HDL-C指标可能优于LDL-C指标。

Study of the relationship between abnormal lipid metabolism and the severity of coronary artery lesion

Objective:To investigate the relationship between abnormal lipid metabolism and coronary artery lesion.Methods:One hundred patients were devided into the normal group,single vessel lesion group,double.At the same time the lipid components were examined and the relationship between serum lipid level and coronary artery lesions were analysed. Results:Compared with the normal group,the total cholestered(TC) and triglyceride(TG) level were not significantly elevated in the other groups.Compared with the normal group,low density lipoprotein cholesterol(LDL-C) level was not significantly elevated while but high density lipoprotein cholesterol(HDL-C) was significantly lowered in the single vessel lesion group and double vessel lesions group. In the trigle vessel lesionsgroup,the low density lipoprotein cholesterol(LDL-C) level was significantly elevated,and the high density lipoprotein cholesterol(HDL-C) was significantly lowered compared with the normal group. Conclusion:The severity of coronary lesions was related with the elevation of LDL-C and the reduction HDL-C. The reduction of HDL-C was better indicator than the elevation of LDL-C.