| 中性粒细胞在ALI/ARDS发生发展中的作用及对策研究进展 |
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| 引用本文： | 贺志高,黄显凯. 中性粒细胞在ALI/ARDS发生发展中的作用及对策研究进展[J]. 创伤外科杂志, 2012, 14(2): 184-187 |
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| 作者姓名： | 贺志高 黄显凯 |
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| 作者单位： | 第三军医大学大坪医院野战外科研究所全军战创伤中心,重庆,400042 |
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| 基金项目： | 军队"十一五"课题 |
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| 摘 要： | 急性肺损伤/急性呼吸窘迫综合征(ALI/ARDS)是由多种炎性递质及效应细胞共同参与,并呈级联放大的炎症继发性弥散性肺实质损伤,以顽固的低氧血症为主要临床表现的病理生理综合征;至今仍是高发病率和高死亡率、难以预防的临床危重症。中性粒细胞在急性肺损伤/急性呼吸窘迫综合征发病中起到至关重要的作用,本文就中性粒细胞在肺损伤中的作用研究及对策进展作一综述。
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| 关 键 词： | 肺损伤 急性呼吸窘迫综合征 中性粒细胞 |
Role of neutrophil in the development of ALI/ARDS |
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| HE Zhi-gao , HUANG Xian-kai. Role of neutrophil in the development of ALI/ARDS[J]. Journal of Traumatic Surgery, 2012, 14(2): 184-187 |
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| Authors: | HE Zhi-gao HUANG Xian-kai |
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| Affiliation: | (Department of ICU,Urumuqi General Hospital of Lanzhou Command,Urumuqi 830000,China) |
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| Abstract: | Acute lung injury/acute respiratory distress syndrome（ALI/ARDS） is a secondary inflammatory lung injury characterized with obstinate hypoxemia,induced by effect of multiple inflammatory medium and effective cells.It has been a critical clinical syndrome with high morbidity rate and high mortality rate.It is well-known that the neutrophils plays a critical role in the development of ALI/ARDS.The present article reviews the advances in the research of the role of neutrophils and the role of neutrophil inhibition in ALI/ARDS. |
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| Keywords: | lung injury acute respiratory distress syndrome neutrophil |
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