Influence of exercise intensity on atrophied quadriceps muscle in the
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| Authors: | Shoji Tanaka Taishi Obatake Koichi Hoshino Takao Nakagawa |
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| Affiliation: | 1) Faculty of Health Sciences, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Japan;2) Department of Rehabilitation, Kanazawa Nishi Hospital, Japan;3) School of Health Sciences, College of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Japan;4) Department of Rehabilitation, Mitsugi General Hospital, Japan |
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| Abstract: | [Purpose] The aim of this study was to determine the effect of resistance training onatrophied skeletal muscle in rats based on evidence derived from physical therapy.[Subjects and Methods] Rats were forced to undergo squats as resistance training for 3weeks after atrophying the rectus femoris muscle by hindlimb suspension for 2 weeks. Theintensity of resistance training was adjusted to 50% and 70% of the maximum lifted weight,i.e., 50% of the one-repetition maximum and 70% of the one-repetition maximum,respectively. [Results] Three weeks of training did not alter the one-repetition maximum,and muscle fibers were injured while measuring the one-repetition maximum and reloading.The decrease in cross-sectional area in the rectus femoris muscle induced by unloading for2 weeks was significantly recovered after training at 70% of the one-repetition maximum.The levels of muscle RING-finger protein-1 mRNA expression were significantly lower inmuscles trained at 70% of the one-repetition maximum than in untrained muscles.[Conclusion] These results suggest that high-intensity resistance training can promoteatrophic muscle recovery, which provides a scientific basis for therapeutic exercisemethods for treatment of atrophic muscle in physical therapy.Key words: Muscle atrophy, Quadriceps muscle, Resistance training |
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