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A French nationwide survey of phototherapy in very preterm and moderately preterm infants
Affiliation:1. Réanimation Néonatale, pôle Femme-Couple-Enfant, CHU Amiens, France;2. PériTox, Laboratoire mixte INERIS, UMR-I 01, UFR de Médecine, Université de Picardie Jules Verne, Amiens, France;1. Department of Pediatric Nephrology, University Hospitals Leuven, Leuven, Belgium;2. PKD Research Group, Department of Cellular and Molecular Medicine, KU Leuven, Leuven, Belgium;3. Department of Pediatrics, ULiège Academic Hospital, Liège, Belgium;4. Department of Pediatric Radiology, University Hospitals Leuven, Leuven, Belgium;1. Université Claude Bernard Lyon 1, Villeurbanne, France;2. Service d''Allergologie et Immunologie clinique, Centre Hospitalier Lyon Sud, Hospices Civils de Lyon, Pierre-Bénite, France;3. Centre International de Recherche en Infectiologie, INSERM U1111, CNRS UMR 5308, UCBL1, ENS de Lyon, Lyon, France;4. Service de Pédiatrie, Pneumologie, Allergologie et Mucoviscidose, Hôpital Femme Mère Enfant, Hospices Civils de Lyon, Bron, France;1. CHU Rouen, Department of Pediatric Emergency, 76000 Rouen, France;2. CHU Rouen, Department of Neonatal Pediatrics, Intensive Care and Neuropediatrics, CHU Rouen, 76000 Rouen, France;3. Addictovigilance Center of Britany and Normandy, CHU Caen, 14000 Caen, France;4. Normandie University, UniRouen, Inserm U 1245, CHU Rouen, 76000 Rouen, France;1. Pediatric and Neonatal Intensive Care Unit, Nantes University Hospital, 38 bld Jean Monnet, Nantes 44000, France;2. Clinical Epidemiology, Clinical Investigation Center (CIC004), University Hospital Centre Nantes, France
Abstract:Phototherapy for jaundice in preterm infants should always be administered in accordance with specific guidelines. However, guidelines on phototherapy in very preterm and moderately preterm infants are currently lacking in France. We performed a nationwide quality improvement study of the management of jaundice in these preterm infants and compared the results with the international guidelines. Of the 275 maternity units initially contacted, 165 (60.0%) replied. Our results showed that clinical practice differs markedly from one unit to another – notably with regard to the prescription, administration, and monitoring of phototherapy and the reference curves used. Even though there is limited evidence on the safety and efficacy of phototherapy in very or moderately preterm infants, a French expert committee should be encouraged to develop consensus guidelines and thus improve quality of care in this setting.
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