兔胫骨骨膜大部分切除对胫骨结构的影响

目的　观察兔胫骨骨膜大部切除后供区骨变化 .方法　新西兰大耳白兔 12只 ,左胫骨手术切除大部骨膜 75mm× 18mm ,约占全胫骨骨膜的 2 / 3,右侧未切除骨膜 .通过X线、骨密度、组织学和生物力学等检测手段 ,比较术后 8,12wk双侧兔胫骨的差异 .结果　骨膜大部切除后的兔胫骨 ,由于干骺血管系统和剩余部位的骨膜血管充分代偿 ,在骨长度、骨密度、骨强度及组织学方面与骨膜完整的兔胫骨无显著差异 (P >0 .0 5 ) .另外骨膜切除后 8wk ,有新的骨膜再生 ,其组织结构与正常骨膜基本相同 .结论　骨膜大部分切除后对供区骨组织无明显影响 .

Effect of subtotal periosteal stripping on architecture of tibia in rabbits

AIM To observe the effects of subtotal periosteal stripping on the architecture of the rabbits' tibia. METHODS A comparison was conducted between the tibia of the rabbit that had been stripped of a greater part of periosteum and the tibia with an intact periosteum, with regard to the length, density, strength and histological findings in 8 and 12 wk after operation. RESULTS The studies revealed similar measurements of the intact periosteum and the stripped one, suggesting the compromise of the vascularization at the donor site had been fully compensated by the invasion of metaphyseal vessels and vessels of the remaining periosteum, resulting in unchanged morphology, density and strength of the donor site bone. Furthermore, regeneration of periosteum at the donor site was observed and the operated periosteum had the same structure as the untouched periosteum 8wk post operation. CONCLUSION Large area periosteum harvesting will not affect the architecture of the bone at donor site.