The importance of slice location on the accuracy of aortic regurgitation measurements with magnetic resonance phase velocity mapping |
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Authors: | George P Chatzimavroudis Peter G Walker John N Oshinski Robert H Franch Roderic I Pettigrew Ajit P Yoganathan |
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Institution: | (1) Cardiovascular Fluid Mechanics Laboratory, School of Chemical Engineering, Institute for Bioengineering and Bioscience, Georgia Institute of Technology, 778 Atlantic Drive, 30332-0100 Atlanta, GA, USA;(2) Department of Mechanical Engineering, University of Leeds, Leeds, UK;(3) Department of Radiology, Frederik Philips, Magnetic Resonance Research Center, Emory University Hospital, Atlanta, GA;(4) Department of Cardiology, Emory University Hospital, Atlanta, GA |
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Abstract: | Although several methods have been used clinically to evaluate the severity of aortic regurgitation, there is no purely quantitative
approach for aortic regurgitant volume (ARV) measurements. Magnetic resonance phase velocity mapping can be used to quantify
the ARV, with a single imaging slice in the ascending aorta, from through-slice velocity measurements. To investigate the
accuracy of this technique,in vitro experiments were performed with a compliant model of the ascending aorta. Our goals were to study the effects of slice location
on the reliability of the ARV measurements and to determine the location that provides the most accurate results. It was found
that when the slice was placed between the aortic valve and the coronary ostia, the measurements were most accurate. Beyond
the coronary ostia, aortic compliance and coronary flow negatively affected the accuracy of the measurements, introducing
significant errors. This study shows that slice location is important in quantifying the ARV accurately. The higher accuracy
achieved with the slice placed between the aortic valve and the coronary ostia suggests that this slice location should be
considered and thoroughly examined as the preferred measurement site clinically. |
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Keywords: | Aortic regurtigation Regurgitant volume Magnetic resonance phase velocity mapping Aortic compliance |
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