| 四种血小板制品滤除白细胞效果的实验研究 |
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| 引用本文： | 韩玮,李伟静,陶涛,宋丽敏,陈民才,卓海龙,于群,王全立. 四种血小板制品滤除白细胞效果的实验研究[J]. 临床输血与检验, 2009, 11(2): 103-106. DOI: 10.3969/j.issn.1671-2587.2009.02.03 |
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| 作者姓名： | 韩玮 李伟静 陶涛 宋丽敏 陈民才 卓海龙 于群 王全立 |
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| 作者单位： | 100071,北京,军事医学科学院附属医院输血科;北京市公安局丰台分局法医检验鉴定所;军事医学科学院野战输血研究所;第二炮兵防护疫环境监测队;军事医学科学院附属医院输血科,北京,100071 |
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| 基金项目： | 首都特色临床医学技术发展研究专项基金 |
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| 摘 要： | 目的观察过滤对血小板的影响,遴选适于过滤的血小板制品。方法对机采血小板、手工浓缩血小板和相应的两种冰冻血小板进行过滤,观察血小板回收率、白细胞去除率和血小板聚集率等多项血小板功能指标。结果机采血小板回收率为86．81％,手工浓缩血小板回收率仅为73．08％;两种冰冻血小板制品损失量达60%～70％;过滤后机采血小板达到去白细胞标准,而手工血小板未达到去白细胞标准;过滤对液态保存血小板制品的功能无明显影响,但手工浓缩血小板功能低于机采血小板。结论冰冻保存的血小板制品不适于去白细胞过滤;手工浓缩血小板制备工艺尚需进一步改进和提高,并研制与之相适应的去白细胞滤器;机采血小板质董拔好．国产滤器可达到去白细胞标准．是当前适于滤除白细胞的血小板制品。
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| 关 键 词： | 白细胞过滤 机采血小板 冰冻血小板 |
Experimental Study on the Effect of Filtration on the Platelet Preparations |
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| HAN Wei,LI Wei-jing,TAO Tao,et al.. Experimental Study on the Effect of Filtration on the Platelet Preparations[J]. Journal of Clinical Transfusion and Laboratory Medicine, 2009, 11(2): 103-106. DOI: 10.3969/j.issn.1671-2587.2009.02.03 |
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| Authors: | HAN Wei LI Wei-jing TAO Tao et al. |
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| Affiliation: | HAN Wei,LI Wei-jing,TAO Tao,et al.Department of Transfusion Medicine,Affiliated Hospital of the Academy of Military Medical Sciences,Beijing 100071 |
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| Abstract: | Objective The effect of filtration on the platelet preparations was observed,and platelet preparations suited to platelet filtration were selected.Method The filtration effect of apheresis platelet,platelets concentration and their relative frozen platelets was studied while observing the platelet recovery rate,leukocyte removal rate,platelet con-centrationrateandvariousplateletfunctionindexes.Results Theplateletrecoveryrateforapheresisplateletwas 86.81%,while manual concentrated platelet was only 73.08%.Th... |
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| Keywords: | Leukocyte filtration Apheresis platelet Frozen platelet |
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