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| 乳腺癌患者化疗前期抑郁焦虑的现况调查和心理+药物干预的疗效评价 | |
| 引用本文： | 唐梅,唐艳,陈秋菊,吴彩霞,李晓利,刘明秀,汪令成,王群.乳腺癌患者化疗前期抑郁焦虑的现况调查和心理+药物干预的疗效评价[J].海南医学,2013,24(16):2352-2356. |
| 作者姓名： | 唐梅 唐艳 陈秋菊 吴彩霞 李晓利 刘明秀 汪令成 王群 |
| 作者单位： | 1. 湖北医药学院附属太和医院普外4科,湖北十堰,442000 2. 茅箭区人民医院急诊科,湖北十堰,442000 3. 湖北医药学院第一临床医学院,湖北十堰,442000 4. 湖北医药学院护理学院,湖北十堰,442000 5. 湖北医药学院第三临床医学院,湖北十堰,442000 6. 湖北医药学院内分泌血管外科,湖北十堰,442000 |
| 基金项目： | 湖北医药学院研究生启动基金 |
| 摘 要： | 目的调查乳腺癌患者化疗前期抑郁焦虑症状发生现况,评估综合心理干预护理联合帕罗西汀疗法对乳腺癌患者焦虑抑郁的临床疗效。方法采用自编问卷、Herth希望量表、汉密尔顿抑郁量表(HAMD)和汉密尔顿焦虑量表(HAMA)对81例已婚女性乳腺癌患者进行调查和测评,将符合纳入标准的64例乳腺癌并抑郁焦虑患者(HAMD评分≥8分且HAMA评分≥7分)随机分为干预组(32例)和对照组(32例)。对照组给予常规护理,干预组在常规护理的基础上,在化疗期接受心理干预护理联合服用帕罗西汀,并对两组化疗前后抑郁焦虑的情况及其化疗效果进行对比分析。结果干预组化疗期Herth、HAMD和HAMA水平分别为(33.94±8.26)分、(15.78±5.24)分、(14.34±5.51)分,与对照组比较(24.74±6.96)分、(24.66±5.23)分、(15.78±4.36)分],除HAMA外,差异均具有显著统计学意义(P<0.01);干预组化疗期Herth、HAMD和HAMA水平与化疗前比较(21.37±6.51)分、(25.10±5.62)分、(17.69±4.93)分],差异均具有显著统计学意义(P<0.01)。干预组化疗期希望水平、抑郁和焦虑总有效率为96.87%、59.37%、46.88%,与对照组比较,除焦虑外,差异均具有统计学意义(P<0.01)。干预组完全缓解率、部分缓解率和总缓解率分别为18.75%,68.75%,87.5%,均高于对照组。 |
| 关 键 词： | 心理干预 帕罗西汀 乳腺癌 抑郁 焦虑 |
Prevalent survey of depression and anxiety and effect of psychological and drug intervention in patients with breast cancer before chemotherapy |
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| TANG Mei,TANG Yan,CHEN Jiu-ju,WU Cai-xia,LI Xiao-li,LIU Ming-xiu,WANG Ling-chen,WANG Qun.Prevalent survey of depression and anxiety and effect of psychological and drug intervention in patients with breast cancer before chemotherapy[J].Hainan Medical Journal,2013,24(16):2352-2356. | |
| Authors: | TANG Mei TANG Yan CHEN Jiu-ju WU Cai-xia LI Xiao-li LIU Ming-xiu WANG Ling-chen WANG Qun |
| Institution: | 5 . 1. The Fourth Department of General Surgery, Taihe Hospital Affiliated to Hubei University of Medicine, Shiyan 442000, Hubei, CHINA; 2. Emergency Department, Maojian District People’s Hospital, Shiyan 442000, Hubei, CHINA; 3. The First Clinical Medical College, Hubei University of Medicine, Shiyan 442000, Hubei, CHINA; 4. College of Nursing, Hubei University of Medicine, Shiyan 442000, Hubei, CHINA; 5. The Third Clinical Medical College, Hubei University of Medicine, Shiyan 442000, Hubei, CHINA; 6. Vascular Surgery, Hubei University of Medicine, Shiyan 442000, Hubei, CHINA |
| Abstract: | |
| Keywords: | Psychotherapy Paroxetine Breast cancer Depression Anxiety |
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