小功率脉冲微波接触者外周血淋巴细胞染色体畸变及微核率观察

对某研究所接触脉冲微波作业的高功率组42人、低功率组(元件组)60人和无微波接触的对照组51人的外周血淋巴细胞染色体畸变及微核进行观察。结果显示,两接触组外周血淋巴细胞微核率异常率、高功率组微核率均显著高于对照组(P<0.01);高功率组染色体畸变率异常者检出率、畸变细胞率、染色体型畸变率均显著高于对照组及元件组(P<0.01);而染色单体型畸变率两接触组与对照组差别均无统计学意义(P>0.05)。在偏相关分析控制年龄因素后,两接触组微核率、染色体型畸变率与工龄无相关性(P=0.451,P=0.270)。说明小功率脉冲微波辐射对人体外周血淋巴细胞染色体及微核形成具有一定不良影响。

Analysis on chromosome aberrations and micronucleus rate in peripheral lymphocytes in workers exposed to low power impulse microwave radiation

To study the effect of low power impulse microwave radiation on chromosome aberrations and micronucleus rate of peripheral lymphocytes then provide a reference data for the health monitoring on occupational exposed workers.42 workers exposed to high power impulse microwave radiation were selected as'high power group',60 workers from element post were exposed to low power impulse microwave radiation were selected as'low power group',51 workers without microwave radiation exposure were selected as controls.Their chromosome aberrations and micronucleus rate in peripheral blood lymphyocytes were observed.Result The detection rate of abnormal micronucleus individuals in both exposed groups and the micronuleus rate of high power group were significantly higher than that of the control group(P<0.01).The detection rate of chromosome aberration positive individuals,the incidence of aberration cells and the aberration rate of chromosomal pattern in high power group were significantly higher than that of both low power group and control group(P<0.01),while the chromatid aberration rates were no significant difference among three groups(P>0.05).After excluding the age factor using partial correlation analysis,the micronucleus rates and chromosome aberration rates in both exposed groups showed no dependability with service length(P=0.451,P=0.270,respectively).The low power impulse microwave radiation may have some negative effect on chromosome aberration and micronucleus formation in peripheral lymphocytes of exposed workers.