| 表皮生长因子受体与肺泡上皮不典型腺瘤样增生的关系 |
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| 引用本文： | 黄谦. 表皮生长因子受体与肺泡上皮不典型腺瘤样增生的关系[J]. 国际病理科学与临床杂志, 2012, 32(1): 84-87 |
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| 作者姓名： | 黄谦 |
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| 作者单位： | 中南大学湘雅二医院病理科,长沙410011;岳阳职业技术学院医学基础部,湖南岳阳414000 |
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| 摘 要： | 肺癌是人类常见的恶性肿瘤,肺腺癌是其主要类型之一.细支气管肺泡癌(bronchioloalveolar lung carcinoma,BAC)是肺腺癌的一个特殊类型.肺泡上皮不典型腺瘤样增生(atypical adenomatous hyperplasia,AAH)可能是BAC或腺癌的癌前病变,甚至是其早期癌.表皮生长...
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| 关 键 词： | 肺癌 肺泡上皮不典型腺瘤样增生 表皮生长因子受体 细支气管肺泡癌 突变 |
Epidermal growth factor receptor and alveolar epithelial atypical adenomatous hyperplasia |
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| HUANG Qian. Epidermal growth factor receptor and alveolar epithelial atypical adenomatous hyperplasia[J]. Journal of International Pathology and Clinical Medicine, 2012, 32(1): 84-87 |
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| Authors: | HUANG Qian |
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| Affiliation: | 1 (1.Department of Pathology,Second Xiangya Hospital,Central South University,Changsha 410011; 2.Department of Basic Medical Science,Yueyang Higher Vocational and Technical College,Yueyang Hunan 414000,China) |
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| Abstract: | Lung cancer is a common malignant tumor and lung adenocarcinoma is the main type of it.Bronchioloalveolar lung carcinoma(BAC) is a special type of lung adenocarcinoma.Research indicates that alveolar epithelial atypical adenomatous hyperplasia(AAH) in BAC or adenocarcinoma may be a precancerous lesion,even in the early stage of cancer.Overexpression and/or mutatioin of epidermal growth factor receptor(EGFR) is closely related to the occurrence,development,invasion and metastasis of lung cancer,especially in non-small-cell lung cancer(NSCLC).But there are few studies reported about EGFR in the precancerous lesion of non-small-cell lung cancer. |
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| Keywords: | lung cancer atypical adenomatous hyperplasia epidermal growth factor receptor bronchioloalveolar lung carcinoma mutation |
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