| 骨肿瘤患者血液LPO、SOD、GSH-PX与GSH临床价值的初步探讨 |
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| 引用本文： | 吴长珠,刘友尧,林建华,朱维钦,吴天中,黄仲驹. 骨肿瘤患者血液LPO、SOD、GSH-PX与GSH临床价值的初步探讨[J]. 肿瘤防治研究, 1994, 0(1) |
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| 作者姓名： | 吴长珠 刘友尧 林建华 朱维钦 吴天中 黄仲驹 |
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| 作者单位： | 福建医学院生化教研室，福建医学院生化附一院，福建医学院生化医学系 |
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| 摘 要： | 本文对２９例恶性骨肿瘤、３８树良性骨肿瘤，２１例非瘤骨疾病患者血浆脂质过氧化物（ＬＰＯ）、全血超氧化物歧化酶（ＳＯＤ），谷胱甘肽过氧化物酶（ＧＳＨ一ＰＸ），及谷胱甘肽（ＧＳＨ）进行测定，结果显示：在恶性，良性骨肿瘤与非瘤骨疾病比较、ＳＯＤ（Ｐ＜０．０１）、ＧＳＨ（Ｐ＜０．０５）均有显著差异。ＬＰＯ值在非瘤骨疾病、良性及恶性骨肿瘤是升高趋势，各组比较无显著差异，（Ｐ＞０．０５）。良性、恶性骨肿瘤与非瘤骨疾病的四个项目进行逐步判别分析、ＬＰＯ，ＳＯＤ二项灵敏性９４．０３％。特异性３８．１％，它可供临床辅助诊断参考。
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| 关 键 词： | 骨肿瘤；脂质过氧化物；超氧化物歧化酶 |
A PRELIMINARY STUDY OF CLINICAL VALUE OF BIOOD LPO,SOD,GSH-PXAND GSH IN PATIENTS WITH OSTEOMA |
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| Wu Changzhu,et al. A PRELIMINARY STUDY OF CLINICAL VALUE OF BIOOD LPO,SOD,GSH-PXAND GSH IN PATIENTS WITH OSTEOMA[J]. Cancer Research on Prevention and Treatment, 1994, 0(1) |
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| Authors: | Wu Changzhu et al |
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| Abstract: | This paper deals with the determination of lipoperoxides (LPO) in plasma, superokide dismustase(SOD),Glutathion peroxidase (GSH-PX) and Glutathion (GSH) in blood in 29 cases withmalignant osteoma, 38 cases with benign osteoma and 21 cases with non-tumorous disease of bone,The results showed that both SOD and GSH differed significantly (P<0.01 for SOD and P<0.05for GSH) in malignant osteoma, benign osteoma and nontumorous disease of bone,while conentof plasma LPO tended to increase in all three groups with no significant difference (P>0. 05). Astepwise discriminant analysis of these four indices in the three groups indicated a sensitivity of94.03% and a specificity of 38. 1% in combined LPO and SOD. This can be used as clinical accessory diagnosis. |
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| Keywords: | Osteoma Lipoperoxides Superoxide dismustase |
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