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Adrenal Gland Leiomyoma in a Child with Acquired Immunodeficiency Syndrome
Authors:Jose A. Jimenez-Heffernan   David Hardisson  Jose Palacios  Manuel Garcia-Viera  Carlos Gamallo  Manuel Nistal
Affiliation: a Department of Pathology, Hospital La Paz, Madrid, Spain
Abstract:An adrenal gland leiomyoma was incidentally found at autopsy in a 2-year-old boy with acquired immunodeficiency syndrome (AIDS). Smooth muscle neoplasms have been described in pediatric AIDS and affect mainly the tracheobronchopulmonary, gastrointestinal, and hepatobiliary systems. An association between Epstein-Barr virus (EBV) and smooth muscle tumors in patients with AIDS has been described. This case is the first leiomyoma to be reported in the adrenal gland of a child with AIDS. EBV genome was demonstrated in the tumor by polymerase chain reaction.
Keywords:acquired immunodeficiency syndrome complications  adrenal gland  child  Epstein-Barr virus  leiomyoma  smooth muscle tumors
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