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Biodistribution and radiation dosimetry of [11C]choline: a comparison between rat and human data

Authors:	Tuula Tolvanen Timo Yli-Kerttula Tiina Ujula Anu Autio Pertti Lehikoinen Heikki Minn Anne Roivainen

Institution:	(1) Turku PET Centre, Turku University Hospital, FI-20521 Turku, Finland;(2) Department of Internal Medicine, Turku University Hospital, FI-20521 Turku, Finland;(3) Radiopharmaceutical Chemistry Laboratory, Turku PET Centre, Turku University Hospital, FI-20500 Turku, Finland;(4) Department of Oncology and Radiotherapy, Turku University Hospital, FI-20521 Turku, Finland;(5) Turku Centre for Disease Modelling, University of Turku, FI-20521 Turku, Finland;

Abstract:	Purpose Methyl-¹¹C-choline (¹¹C]choline) is a radiopharmaceutical used for oncological PET studies. We investigated the biodistribution and biokinetics of ¹¹C]choline and provide estimates of radiation doses in humans.

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