| 16例结直肠癌骨转移患者的循证治疗 |
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| 引用本文： | 常春. 16例结直肠癌骨转移患者的循证治疗[J]. 中国医疗前沿, 2011, 6(9): 50-51 |
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| 作者姓名： | 常春 |
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| 作者单位： | 广东省梅州市嘉应学院医学院附属医院,514031 |
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| 摘 要： | 目的查找循证医学证据,为16例结直肠癌骨转移患者制定合理的治疗方案。方法针对患者的临床问题,以metastatic colorectal cancer,RCT,human,systematic review,meta-analysis等为检索词,电子检索Cochrane图书馆（2010年第1期）、EMBASE（2005,1-2010,12）和Black Well electronic journals（2005,1-2010,12）查找相关的系统评价、随机对照试验等,并对所获得证据进行质量评价。结果从Cochrane临床试验中心登记库查到临床对照15篇,从EMBASE及Black Well electronic journals检索到Meta分析10篇,随机对照试验8篇,结果显示对转移性结直肠患者进行化疗可延缓病情的发展,提高患者的生存率,据此,结合医生经验及患者意愿,对该16例患者进行化疗及其他支持治疗,患者临床症状好转,生活质量提高。结论我们运用循证医学证据为16例结直肠癌骨转移患者选择了合理的治疗方案,但化疗的毒性、对患者生活质量的影响及病情症状的控制程度还需要进一步的高质量、大样本的随机对照试验研究。
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| 关 键 词： | 结直肠癌 骨转移 循证治疗 |
Evidence-Based Treatment for 16 Metastatic Colorectal Cancer in Patients |
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| Abstract: | Objective Methods of evidence-based medicine were used to make a reasonable treatment plan concerning metastatic colorectal cancer in patients.Methods After clinical problems were put forward,evidence was collected from first issue(2010,1),Cochrane Library,EMBASE(2005,1-2010,12),Black Well electronic journals(2005,1-2010,12).Subject words: Metastatic colorectal cancer,RCT,human,systematic review,meta-analysis.Results A total of 8 RCTs,15 clinical trials,and 10 meta-analysis were identified.a rational treatm... |
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| Keywords: | Metastatic colorectal cancer Evidence-based treatment |
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