Glassy cell carcinoma of the urethra |
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Authors: | Weissbart Steven J Bianco Fernando J Sotelo Tiffany Atalla Mohamed A Sesterhenn Isabell A Jarrett Thomas W |
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Affiliation: | Department of Urology, George Washington University School of Medicine and Health Sciences, Washington, DC, USA. |
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Abstract: | Glassy cell carcinoma is a poorly differentiated form of adenosquamous carcinoma that has never been reported in the urinary tract. We present the first case of primary glassy cell carcinoma of the urethra in a 48-year-old woman. She presented with a newly developed bulky mass protruding from her urethra. A biopsy of this mass revealed sheets of large polygonal cells with a "ground-glass" cytoplasm among a heavy inflammatory infiltrate, establishing the diagnosis of glassy cell carcinoma of the urethra. Treatment of her tumor included a combined surgical and chemotherapeutic approach. |
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