A possible pathogenic role of CD8+ T cells and their derived cytokine, IL-16, in SLE |
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| Authors: | Sekigawa I Matsushita M Lee S Maeda N Ogasawara H Kaneko H Iida N Hashimoto H |
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| Affiliation: | Department of Medicine, Juntendo University Izu-Nagaoka Hospital, Shizuoka, Japan. |
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| Abstract: | Current investigations into the role of CD8+ T cells and their derived cytokine, interleukin (IL)-16, in the induction of CD4+ T cell abnormalities in systemic lupus erythematosus (SLE) were reviewed and discussed on the basis of results mainly obtained in our laboratory. |
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