| 帕利哌酮缓释片治疗急性期精神分裂症患者的临床疗效比较 |
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| 引用本文： | 梁烨.帕利哌酮缓释片治疗急性期精神分裂症患者的临床疗效比较[J].中国新药杂志,2011(24). |
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| 作者姓名： | 梁烨 |
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| 作者单位： | 佛山市顺德区伍仲珮纪念医院; |
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| 基金项目： | 佛山市科学技术局课题(201008212) |
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| 摘 要： | 目的:研究帕利哌酮缓释片治疗精神分裂症急性期患者的临床疗效和安全性。方法:76例急性期精神分裂症患者随机分成两组,每组38例,治疗组服用帕利哌酮缓释片,对照组服用国产奥氮平片,分别于治疗前和治疗后04,,7,14,28,42 d评定临床疗效、社会功能及不良反应。结果:治疗组和对照组7～14 d显效率分别为89.47%和60.52%(P<0.05),治疗组和对照组14～21 d显效率分别为97.37%和78.95%。结论:帕利哌酮缓释片治疗精神分裂症急性期患者的疗效略优于奥氮平片。
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| 关 键 词： | 帕利哌酮缓释片 急性期 精神分裂症 |
A clinical comparative study on paliperidone ER in treating acute phase schizophrenia patients |
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| LIANG Ye.A clinical comparative study on paliperidone ER in treating acute phase schizophrenia patients[J].Chinese Journal of New Drugs,2011(24). |
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| Authors: | LIANG Ye |
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| Institution: | LIANG Ye(Clinic of Wuzhongpei Memorial Hospital of Shunde in Foshan,Shunde 528333,China) |
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| Abstract: | Objective: To investigate the clinical efficacy and safety of paliperidone extended-release(ER) in the treatment of schizophrenia patients in the acute phase.Methods: Totally 76 schizophrenia patients in the acute phase were randomly divided into 2 groups(n=38 in each group),and treated with paliperidone ER tablets or domestic olanzapine(control).The efficacy,untoward effects,and the personal and social functions were evaluated before treatment and 0,4,7,14,21,28 and 42 days after treatment.Results: At 7~14... |
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| Keywords: | paliperidone extended-release tablet acute period schizophrenia |
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