| 野金柴提取物对心血管系统的作用 |
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| 引用本文： | 梁颖敏,侯少贞,黄松,刘丹丹,赖小平.野金柴提取物对心血管系统的作用[J].中国新药杂志,2011(15). |
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| 作者姓名： | 梁颖敏 侯少贞 黄松 刘丹丹 赖小平 |
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| 作者单位： | 广州中医药大学新药开发研究中心; |
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| 摘 要： | 目的:考察野金柴提取物对心血管系统的作用。方法:分别通过耐缺氧实验、尾静脉注射垂体后叶素方法、耳廓微循环法、双肾双夹肾血管性高血压模型依次考察野金柴提取物的抗应激作用、对急性心肌缺血的保护作用、对微循环的作用和降压作用。结果:野金柴提取物组能延长缺氧小鼠的死亡时间,降低心肌缺血小鼠血清AST,CK及LDH-L水平,显著提高微循环灌注量,但对肾血管性高血压模型小鼠的降压效果不明显。结论:野金柴提取物对心血管系统有一定保护作用。
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| 关 键 词： | 野金柴提取物 耐缺氧 急性心肌缺血 耳廓微循环 降压 |
Cardiovascular effects of Lithocarpus polystachyus extracts |
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| LIANG Ying-min,HOU Shao-zhen,HUANG Song,LIU Dan-dan,LAI Xiao-ping.Cardiovascular effects of Lithocarpus polystachyus extracts[J].Chinese Journal of New Drugs,2011(15). |
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| Authors: | LIANG Ying-min HOU Shao-zhen HUANG Song LIU Dan-dan LAI Xiao-ping |
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| Institution: | LIANG Ying-min,HOU Shao-zhen,HUANG Song,LIU Dan-dan,LAI Xiao-ping(Research & Development Center of New Drugs,Guangzhou University of Chinese Medicine,Guangzhou 510006,China) |
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| Abstract: | Objective: To investigate the cardiovascular effects of Lithocarpus polystachyus extracts.Methods: The anti-stress effect was observed in mouse anti-anoxia experiment.The protective effect on acute myocardial ischemia was evaluated after intravenous injection of pituitrin in rats.The effect on microcirculation was observed by measuring auricle blood flow in mice.The effect on hypertension was determined in two-kidney two-clip(2K2C) renovascular hypertensive rats.Results: Lithocarpus polystachyus extracts pr... |
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| Keywords: | Lithocarpus polystachyus extracts anti-anoxia acute myocardial ischemia auricle microcirculation depressurization |
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