| 藏药大籽獐牙菜不同提取部位的抗菌活性 |
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| 引用本文： | 熊成文,林鹏程.藏药大籽獐牙菜不同提取部位的抗菌活性[J].中国新药杂志,2011(8). |
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| 作者姓名： | 熊成文 林鹏程 |
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| 作者单位： | 青海民族大学;青海省药品检验所; |
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| 摘 要： | 目的:研究并比较大籽獐牙菜不同提取部位的抗菌作用。方法:以不同极性溶剂萃取大籽獐牙菜乙醇提取物,得石油醚提取物、乙酸乙酯提取物、正丁醇提取物及萃取后物质等不同极性部位。以金黄色葡萄球菌、大肠杆菌、沙门菌、枯草芽孢杆菌、白色念珠菌为试验对象,采用平皿打孔灌药法比较大籽獐牙菜不同提取部位的抗菌作用。结果:大籽獐牙菜的石油醚部位、乙酸乙酯部位和正丁醇部位均具有一定的抗菌作用,而萃取后部位没有抗菌作用,其抗G+菌活性比较:乙酸乙酯部位>石油醚部位>正丁醇部位;抗G-菌作用:正丁醇部位>乙酸乙酯部位>石油醚部位;抗真菌活性比较:乙酸乙酯部位>石油醚部位>正丁醇部位。结论:大籽獐牙菜能有效抑制金黄色葡萄球菌、大肠埃希菌、沙门氏菌、枯草芽孢杆菌、白色念珠菌,具有广谱抗菌作用。大籽獐牙菜的抗菌作用不限于一个部位,而是通过多种有效成分、多个环节、多种途径发挥协调作用产生抗菌功效。
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| 关 键 词： | 大籽獐牙菜 提取物 抗菌活性 |
Antimicrobial activities of different extracts from Swertia macrosperma C.B.Clark |
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| XIONG Cheng-wen,LIN Peng-cheng.Antimicrobial activities of different extracts from Swertia macrosperma C.B.Clark[J].Chinese Journal of New Drugs,2011(8). |
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| Authors: | XIONG Cheng-wen LIN Peng-cheng |
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| Institution: | XIONG Cheng-wen1,2,LIN Peng-cheng1(1 Qinghai University for Nationalities,Xining 810006,China,2 Qinghai Institute for Drug Control,Xining 810016,China) |
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| Abstract: | Objective:To determine and compare the antimicrobial activities of extracts from Swertia macrosperma C.B.Clark.Methods: To search for the active components,the systematic solvent methods were used to get the petroleum,ethyl acetate and n-butylalcohol extracts,and the residues after extraction.Staphylococcus aureus,Escherichia coli,Salmonella,Bacillus subtilis,and Candida albicans were used in the antimicrobial experiments.Antimicrobial activities of different kinds of extracts from Swertia macrosperma C.B.C... |
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| Keywords: | Swertia macrosperma C B Clark extract antimicrobial activity |
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