| 黄芪注射液对小鼠骨髓细胞增殖周期的影响 |
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| 引用本文： | 祝晓玲,祝彼得. 黄芪注射液对小鼠骨髓细胞增殖周期的影响[J]. 中药材, 2000, 23(10): 625-627 |
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| 作者姓名： | 祝晓玲 祝彼得 |
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| 作者单位： | 1. 华西医科大学,成都,610041
2. 成都中医药大学,成都,610075 |
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| 摘 要： | 采用骨髓细胞体外培养以及流式细胞仪等实验血液学方法。研究黄芪注射液（ＡＭＩ）对正常和贫血小鼠骨髓细胞增殖周期的影响。终浓度为４０ｕｇ／ｍｌ的ＡＭＩ以及终浓度为４０ｕｇ／ｍｌ、４００ｕｇ／ｍｌ的ＡＭＩ加入培养体系中可分别促进正常或贫血小鼠骨髓细胞进入增殖活跃期（Ｐ〈０．０５），提示一定浓度的ＡＭＩ可以增强小鼠的造血功能。
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| 关 键 词： | 黄芪注射液 骨髓细胞 细胞增殖周期 实验研究 |
| 修稿时间： | 2000-05-08 |
Effect of AMI on Proliferative Cycle Phase of Bone Marrow Cells in Mice |
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| Zhu Xiaoling,Zhu Bide. Effect of AMI on Proliferative Cycle Phase of Bone Marrow Cells in Mice[J]. Journal of Chinese medicinal materials, 2000, 23(10): 625-627 |
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| Authors: | Zhu Xiaoling Zhu Bide |
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| Affiliation: | West China University of Medical Sciences, Chengdu 610041. |
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| Abstract: | By using culture of bone marrow cells in vitro and flowcytometry, effect of Astragalus membranaceus injection (AMI) on proliferative cycle phase of bone marrow cells in normal and anemic mice was studied. AMI 40 micrograms/ml (concentration in culture system) can promote normal murine bone marrow cells (BMC) entering proliferative cycle phase (S + M/G2 phase), so do AMI 40 micrograms/ml and AMI 400 micrograms/ml to anemic murine BMC. The results suggested AMI maybe enhance hematopoietic function in mice. |
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| Keywords: | Astragalus membranaceus injection Bone marrow cells Cell cycle Hematopoiesis Mice |
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