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Treatment of idiopathic sclerosing inflammation of the orbit (myositis) with infliximab |
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| Authors: | Sven Sahlin Börje Lignell Maria Williams Maryam Dastmalchi Abiel Orrego |
| Affiliation: | 1. St Erik’s Eye Hospital, Karolinska Institute, Stockholm, Sweden;2. ?HS, Mariehamn, ?land, Finland;3. Department of Rheumatology, Karolinska Hospital and Institute, Stockholm, Sweden;4. Department of Pathology, Karolinska Hospital and Institute, Stockholm, Sweden |
| Abstract: | Purpose: We report the successful use of infliximab in a young patient with idiopathic sclerosing orbital inflammation (myositis). Methods: We describe the patient’s medical records and review the literature. Results: Idiopathic myositis in this patient could not be satisfactorily treated with corticosteroids or chemotherapy. Biopsy showed sclerosing orbital inflammation. The patient had a prompt and sustained response with infliximab and methotrexate treatment. Conclusions: Infliximab and methotrexate might be considered in patients with idiopathic sclerosing orbital inflammation (myositis). |
| Keywords: | idiopathic orbital inflammation infliximab myositis sclerosing orbital inflammation |