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Pulmonary non-infectious diseases in common variable immunodeficiency |
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| Authors: | Bron C Catherinot E Cadranel J Oksenhendler E Rivaud E Couderc L-J |
| Affiliation: | aService de pneumologie, hôpital Foch, 40, rue Worth, 92150 Suresnes, France;bService de pneumologie, hôpital Tenon, 4, rue de la Chine, 75020 Paris, France;cService d’immunologie clinique, hôpital Saint-Louis, 1, avenue Claude-Vellefaux, 75475 Paris cedex 10, France;dFaculté de médecine Paris-Île-de-France-Ouest, université de Versailles–Saint-Quentin-en-Yvelines, 9, boulevard d’Alembert, 78280 Guyancourt, France;eUPRES EA 220, faculté Paris-Île-de-France-Ouest, 11, rue Guillaume-Lenoir, 92150 Suresnes, France |
| Abstract: | Few studies have described pulmonary non-infectious diseases (PNID) in patients with common variable immunodeficiency (CVID). Indeed the most frequent complications in these patients are infectious. The aim of our study is to analyze the characteristics of PNID in a retrospective study of patients with CVID of two pneumology departments in Paris (France), from 1990 to 2008. PNID was observed in 11 patients. Mean immunoglobulin serum level was 3.46 g/L. The PNID observed were: arteriovenous pulmonary fistula: three; interstitial lung disease: three; asthma: two; mediastinal lymphadenopathy: four; emphysema: one; mesothelioma: one. Our study outlines the broad spectrum of pulmonary manifestations related to CVID. Clinicians should be aware of the diagnosis of PNID even in patients without classic infectious manifestations. |
| Keywords: | Mots clé s: Hypogammaglobuliné mie Dé ficit immunitaire commun variable Fistule arté rioveineuse pulmonaire Pneumopathie interstitielle lymphoï de |
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