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Correction de l’hypoxémie d’exercice chez le BPCO : variabilité des réponses, enjeux et problèmes posés dans le cadre de la réhabilitation respiratoire
Authors:A Varray  N Héraud  F Durand  C Préfaut
Institution:aEA 2991 Movement to health (M2H), université Montpellier 1, Euromov, 700, avenue du Pic-Saint-Loup, 34090 Montpellier, France;bGroupe Fontalvie, Naturopôle, bâtiment D, 3, boulevard de Clairfont, 66350 Toulouges, France;cLaboratoire sport, santé, altitude, UFR STAPS, université de Perpignan l’Ermitage, 66120 Font-Romeu-Odeillo-Via, France;dInserm, U 1046, physiologie et médecine expérimentale du cœur et des muscles, université Montpellier 1, CHU Arnaud de Villeneuve, 371, avenue du Doyen-Giraud, 34295 Montpellier cedex 5, France
Abstract:

Aim

To define in chronic obstructive pulmonary disease patients (COPD) moderately hypoxemic in resting conditions, if controlled acute oxygen supplementation was always able to increase exercise tolerance when partial oxygen saturation SpO2 was corrected.

Results

In hyperoxia, endurance time (TLIM) was significantly and consistently increased in 14 COPD (+68%) and decreased in seven others (–36%). These two subgroups exhibited no difference in resting values or in their disease severity. COPD with a decreased TLIM under hyperoxic conditions had an abnormal response to O2: unchanged cardiac output and ventilation, increased breathing frequency.

Conclusion

This work shows that acute O2 supplementation responses in COPD are not univocal, either on exercise tolerance or cardio-respiratory variables typically affected by hyperoxia.
Keywords:Mots clé  s: Thé  rapie par l&rsquo  exercice/mé  thodes  Tolé  rance à  l&rsquo  exercice  Oxygè  ne/utilisation thé  rapeutique  Consommation d&rsquo  oxygè  ne/physiologie  Maladie pulmonaire  Obstruction chronique
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