记忆合金网二期成形人工气管实验研究

目的寻找一种能与自体气管完全愈合为一体的人工气管。方法将20只犬随机分为带蒂组和不带蒂组，经二期手术成形制成“三明治”式人工气管。置换6cm长颈部气管，观察其生存期、吻合口有无狭窄等。结果带蒂组术后除1只出现吻合口狭窄，2只出现吻合口感染外，其余7只生活质量好。不带蒂组犬术后4周内全部死于吻合口狭窄和感染。结论带蒂记忆合金网二期成形人工气管基本可与自体气管融为一体．成为自体气管的一部分。此种人工气管可以应用到临床。

Experimental study of replacement of artificial tracheal prosthesis by two-stage procedure with memory-alloy mesh

Objective: To make an artificial trachea, which can really healed with native trachea. Methods: 20 dogs are randomized into a pedicle group and a nonpedicle group. 6 cm cervical trachea was resected and replaced with "sandwich" artificial trachea made from memory alloy meshes by two-stage operative procedure. Survival period and stenosis of anastomosis were recorded. Results: Seven dogs in pedicle group survived well and another three were dead. The cause of death was anastomosis stricture in 1 and infection in 2. All dogs in nonpedicle group were dead within four weeks because of stenosis or infection. Conclusion: Two-stage operative pedicle "sandwich" artificial trachea made from memory alloy mesh is up to now the closest artificial trachea to human native trachea. It could be applied clinically.