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| 同种异体脱钙骨基质结合自体红骨髓修复家兔骨缺损的实验研究 | |
| 引用本文： | 王钢,邓向东,王太增,金耀清. 同种异体脱钙骨基质结合自体红骨髓修复家兔骨缺损的实验研究[J]. 中国医科大学学报, 1993, 0(3) |
| 作者姓名： | 王钢 邓向东 王太增 金耀清 |
| 作者单位： | 中国医科大学附属第一医院骨科(王钢，邓向东，王太增)，中国医科大学附属第一医院骨科(金耀清) |
| 摘 要： | 实验用20只成年家兔做为动物模型。在双侧桡骨中段造成一骨缺损,右侧为实验组,植入复合骨移植物;左侧为对照组,单数家兔缺损处植入异体脱钙骨(aDBM),双数家兔植入自体松质骨(ACB)。结果:经组织染色镜下观察证实了aDBM可诱导间质细胞分化成骨细胞并形成新骨,经术后X线平片评分,~(99)Tc—MDP骨闪烁计数得出:实验组新骨形成量高于aDBM组和ACB组。 |
| 关 键 词： | 骨移植 脱钙骨基质 诱导成骨 |
EXPERIMENTAL ANALYSIS OF ALLOGENIC EONE MATRIX SUPPLEMENTED WITH AUTOGENIC EONE MARROW REPAIRING BONE DFFECTS OF RABBIT |
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| Wang Gang,Deng Xiangdong,Wang Taizeng. EXPERIMENTAL ANALYSIS OF ALLOGENIC EONE MATRIX SUPPLEMENTED WITH AUTOGENIC EONE MARROW REPAIRING BONE DFFECTS OF RABBIT[J]. Journal of China Medical University, 1993, 0(3) | |
| Authors: | Wang Gang Deng Xiangdong Wang Taizeng |
| Abstract: | A segmental tone defect was made in middle shaft of bilateral radii of twenty adult rabbits.A composite bone graft was implanted in right bone defect, taking as experimental group.Left limb was taken as control group.Allogenic decalcificated bone matrix (aDBM) was implanted in bone defect in the odd number rabbits, and autogenic concellous bone(ACB)implanted in bone defect in the even number rabbits. It was histologically demonstrated that DBM induced mesenchymal cells proliferating, differentiating into esteoblasts and formating new bone; X-ray plain film scoring and ~(99)Tc-MDP scintigraphy and scintillation count showed that the quantity of new bone in experimental group was higher than that in both aDBM group and ACB group |
| Keywords: | bone grafing decalcificated bone matrix bone formation. |
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