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Research review Neuropeptides and traumatic brain injury
引用本文:王国良,朱诚. Research review Neuropeptides and traumatic brain injury[J]. 中国人民解放军军医大学学报, 1992, 0(1)
作者姓名:王国良  朱诚
作者单位:Department of Neurosurgery Changzheng Hospital,Second Military Medical University,Shanghai 200003,Department of Neurosurgery,Changzheng Hospital,Second Military Medical University,Shanghai 200003
摘    要:It has been proved that endogenous opioids play an important pathophysiological role inthe lesions secondary to central nervous system trauma.Opiate antagonists and opioid antisera havebeen found to improve the outcome of experimental brain injury,Thyrotropin-releasing hormone(TRH),which appears to act in part as a functional antagonist of opioid system,has also beenproved to be effective in the treatment of experimental brain injury.The developments of these as-pects in our laboratory are reviewed.


Research review Neuropeptides and traumatic brain injury
Wang Guoliang Zhu Cheng. Research review Neuropeptides and traumatic brain injury[J]. Journal of Medical Colleges of PLA(China), 1992, 0(1)
Authors:Wang Guoliang Zhu Cheng
Affiliation:Wang Guoliang Zhu Cheng Department of Neurosurgery,Changzheng Hospital,Second Military Medical University,Shanghai 200003
Abstract:It has been proved that endogenous opioids play an important pathophysiological role in the lesions secondary to central nervous system trauma.Opiate antagonists and opioid antisera have been found to improve the outcome of experimental brain injury,Thyrotropin-releasing hormone (TRH),which appears to act in part as a functional antagonist of opioid system,has also been proved to be effective in the treatment of experimental brain injury.The developments of these as- pects in our laboratory are reviewed.
Keywords:beta-endorphins  dynorphins  thyrotropin-releasing hormone  brain injuries
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