| 中等剂量阿糖胞苷治疗急性非淋巴细胞白血病的毒副反应观察 |
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| 引用本文： | 盛蓉 邢佩霓. 中等剂量阿糖胞苷治疗急性非淋巴细胞白血病的毒副反应观察[J]. 临床血液学杂志, 1994, 7(3): 110-111 |
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| 作者姓名： | 盛蓉 邢佩霓 |
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| 作者单位： | 陕西省人民医院血液科 710068(盛蓉，邢佩霓，王无忌)，陕西省人民医院血液科 710068(李梅生) |
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| 摘 要： | 用中等剂量阿糖胞苷(IDAra-C,1g/m~2 q12h×6或10)治疗10例急性非淋巴细胞白血病病人,其毒副反应包括发热、恶心、呕吐、脱发、血细胞减少和阿糖胞苷综合征。这些毒副反应均为可逆性并可以耐受。血细胞减少期从治疗开始在7～21天之间,没有发生早期死亡,也没有观察到中枢神经系统的毒副反应发生。我们认为中等剂量阿糖胞苷优于高剂量阿糖胞苷。
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| 关 键 词： | 阿糖胞苷 白血病 急性非淋巴细胞 毒性 |
The Observation of the Toxicity of Intermediate Dose Cytocine |
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| Sheng Rong.Xing Pcini.Wang Wuji et alArabinoside for Acute Non-Lymphocytic Leukemia The people''s hospital of Shanxi Province. The Observation of the Toxicity of Intermediate Dose Cytocine[J]. Journal of Clinical Hematology, 1994, 7(3): 110-111 |
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| Authors: | Sheng Rong.Xing Pcini.Wang Wuji et alArabinoside for Acute Non-Lymphocytic Leukemia The people''s hospital of Shanxi Province |
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| Affiliation: | Sheng Rong.Xing Pcini.Wang Wuji et alArabinoside for Acute Non-Lymphocytic Leukemia The people's hospital of Shanxi Province |
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| Abstract: | The patients with acute non-lymphocytic leukemia (ANLL) were treated with intermediate dose cytocine arabinoside(IDAra-c, lg/m2, 6 or 10). The toxicity including f ever, nausia, vomiting, hair loss,pancytopenia and cytocine arabi-noside syndrome was reversible and tolerable. The pancytopenia period ranged from 7- 21 days, after beginning of treatment, none early death occurred, none central nerve system toxicity occurred We think that IDAra-c is better that high dose cytocine arabinoside. |
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| Keywords: | Ara-C ANLL Intermediate Dose |
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