艾滋病病毒母婴传播阻断效果分析

目的分析艾滋病患病率较高的河南省某县婚龄妇女及孕妇、产妇的人类免疫缺陷病毒（HIV）感染状况;探讨实行多种干预措施后的效果及科学、简单、经济的阻断HIV经母婴传播的评价方法.方法采取整群抽样方法,对该县婚龄妇女及孕产妇进行连续4年HIV的监测,采取实验流行病学研究方法对不同目标人群采取不同干预措施（提供咨询、暂缓结婚、自愿终止妊娠、母婴抗病毒药物服用）;并对HIV阳性人群进行描述性研究.对HIV感染产妇所分娩的婴儿分别进行0、9和18个月时随访与检测;初步对产妇和婴儿的药物阻断效果进行评价.结果 4年来,共对婚龄妇女13693人、孕妇32155人、产妇11367人进行HIV抗体检测;其中确认HIV阳性的婚龄妇女39人、孕妇112人、产妇81人;81名产妇所分娩的婴儿85人中,19名满18月龄婴儿HIV抗体检测阴性,其余仍在随访中.结论采用多种阻断艾滋病经母婴途径传播的干预模式,取得一定效果.

Analysis on AIDS PMTCT in a county of Henan province

Objective To analyze the situation of HIV infection in pregnant women,lying-in women and marriage women of certain county where HIV prevalence rate was higher in Henan.To discuss the effect that some control and prevention steps had been carried out,and to set up a sort of science,simple and economy evaluation method about PMTCT.Methods By cluster sampling way and experimental epidemiology way,we carried out HIV surveillance lasted four years among pregnant woman,lying-in woman and marriage woman in a certain county of Henan province,had carried out different control and prevention steps for different HIV positive persons(providing refer,suggesting to respite marriage,selecting to stop pregnancy voluntarily,taking nevirapine(NVP) for mother and child),and had carried out HIV follow up and test for the children of HIV positive lying-in woman in 0,9 and 18 months,respectively.Results 13?693 marriage women,32155 pregnant women and 11?367 lying-in women had been tested by the end of 2004 and the affirmed HIV positive was 39,112 and 81,respectively.85 infants had birthed by 81 HIV positive lying-in women,19 infants had test HIV negative at the end of 18th months.The other infants were following up continued.Conclusion A PMTCT mode was set up in the county.The route was efficiently cut off though mother to child transmitting AIDS in this county.