调气活血法治疗慢性萎缩性胃炎临床观察

目的观察调气活血法治疗慢性萎缩性胃炎的临床疗效。方法将60例慢性萎缩性胃炎患者随机分为治疗组和对照组,每组30例;治疗组采用调气活血法治疗,对照组予胃复春治疗;两组疗程均为6个月,观察临床疗效、病理疗效及主要症状体征变化情况。结果①治疗组、对照组临床总有效率分别为83.3%、70.0%;组间临床疗效比较,差异有统计学意义（P〈0.05）。②治疗组胃黏膜萎缩、肠上皮化生、异型增生总有效率分别为80.0%、72.2%、46.7%,对照组分别为60.0%、50.0%、38.5%;组间比较,胃黏膜萎缩疗效和肠上皮化生疗效差异有统计学意义（P〈0.05）。③治疗前后组内比较,治疗组胃脘胀满、胃脘痛、胃脘嘈杂、嗳气泛酸、大便稀薄、乏力积分及总分差异有统计学意义（P〈0.05）,对照组胃脘痛、胃脘嘈杂、嗳气泛酸、大便稀薄、乏力积分及总分差异有统计学意义（P〈0.05）;组间治疗后比较,胃脘胀满、饮食减少、恶心呕吐、口苦口干积分及总分差异有统计学意义（P〈0.05）。结论调气活血法治疗慢性萎缩性胃炎疗效良好,不仅能改善患者的临床症状,对部分胃黏膜萎缩、肠上皮化生及异型增生也有治疗作用。

Clinical observation on qi-regulation and blood-activation method in the treatment of chronic atrophic gastritis

Objective To observe the clinical efficacy of qi-regulation and blood-activation method in treating chronic atrophic gastritis （ CAG）. Methods Sixty cases were randomized into two groups： treatment group in which 30 cases were treated by regulating qi and activating blood method, and control group in which 30 cases were treated by ＂ Weifuchuan＂, with the course of 6 months. The clinical efficacy, pathological effect and symptoms and signs were observed. Results ① The overall effective rate was 83.3% in the treatment group and 70.0% in the control group, with a difference in clinical efficacy between the two groups （ P 〈 0.05 ）. ② The total effective rates of atrophic gastric mucosa, intestinal metaplasia and dysplasia were 80.0% , 72.2% , 46.7% in treatment group respectively, and were 60.0%, 50.0%, 38.5% in control group; there were significant differences in atrophic gastric mucosa and intestinal metaplasia between the two groups （ P 〈 0.05 ）.③ Before and after treatment, there were significant differences in the distension, pain, gastric upset, acid regurgitation, loose stool, weakness, total score in treatment group （ P 〈 0.05 ）, and there were significant differences in epigastric pain, gastric upset, acid regurgitation, loose stool, weakness, total score in control group（ P 〈 0.05 ） ; after treatment, there were significant differences in distension, poor appetite, nausea and vomiting, bitter taste and dry mouth and total score between the two groups （ P 〈 0.05 ）. Conclusion Qi-regnlation and blood-activation method is effective to treat CAG. It can improve the clinical symptoms and treat atrophic gastric mucosa, intestinal metaplasia and dysplasia.