氯沙坦与福辛普利治疗原发性高血压的疗效观察

目的对比观察氯沙坦与福辛普利治疗原发性高血压效果。方法随机选择我社区2009年8月—2011年8月原发性高血压患者79例,分成两组,治疗组45例,给予氯沙坦药物治疗;对照组34例,给予福辛普利药物治疗。观察两组舒张压、收缩压、心率控制情况,治疗效果和不良反应发生率。结果随访9～13个月,治疗组患者舒张压68～75mmHg,收缩压105～127mmHg,心率71～79次/min;显效32例,有效12例,无效1例;出现头晕1例,疲劳1例,不良反应发生率为4.4%。对照组患者舒张压81～94 mmHg,收缩压134～151 mmHg,心率77～86次/min;显效16例,有效11例,无效7例;出现恶心2例,头晕1例,疲劳1例,不良反应发生率为11.8%。两组舒张压、收缩压、心率控制情况比较,差异均有统计学意义（P〈0.05）;两组治疗效果比较,差异均有统计学意义（P〈0.05）;两组不良反应发生率比较差异均有统计学意义（P〈0.05）。结论氯沙坦治疗原发性高血压,血压、心率控制情况较好,有效率较高,不良反应发生率较低,值得临床推广应用。

Losartan and Fosinopril Comparative Observation of the Treatment of Essential Hypertension

Objective Treatment of essential hypertension effects of losartan and fosinopril be a comparative analysis.Methods Randomly selected communities from August 2009 to August 2011 79 patients with essential hypertension,divided into A,B two group A treatment group of 45 patients given losartan medication;B group,the control group patients 34name given fosinopril medication.Results A group treatment group patients after treatment,systolic and diastolic blood pressure were significantly lower than in group B,the heart rate is lower than in group B patients,the treatment efficiency than in group B than in group B,the incidence of adverse reactions.Conclusion Losartan treatment of essential hypertension,have higher efficiency.