| 经直肠超声结合前列腺特异性抗原密度检测对前列腺癌的诊断价值 |
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| 引用本文： | 沈伟东,查月琴,王阿军,侯建全,欧阳俊.经直肠超声结合前列腺特异性抗原密度检测对前列腺癌的诊断价值[J].苏州大学学报(自然科学版),2008,28(5). |
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| 作者姓名： | 沈伟东 查月琴 王阿军 侯建全 欧阳俊 |
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| 作者单位： | [1]苏州大学附属第一医院超声科,江苏苏州215006 [2]苏州大学附属第一医院泌尿外科,江苏苏州215006 |
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| 基金项目： | 苏州市科技局资助项目 |
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| 摘 要： | 目的探讨经直肠超声结合前列腺特异性抗原密度（PSAD）与移行区校正的前列腺特异性抗原密度（PSATZ）对前列腺癌的诊断价值。方法选取经病理证实的前列腺癌（PCa）与良性前列腺增生（BPH）患者各19例,就其声像图特征、前列腺特异性抗原（PSA）及其相应的PSAD和PSATZ进行分析比较。结果19例PCa中,超声发现14例,5例仅提示为BPH。14例中,1例为弥漫性病变,13例为结节性病变。共检出16个结节,其中低回声结节占75%（12/16）,高回声及混合回声占25%（4/16）;13个结节位于外周区,3个位于移行区。PCa的PSA值为8.61-98.65ng/ml,平均（48.79±25.34）ng/ml;BPH的PSA值为0.58-28.36ng/ml平均（9.73±8.19）ng/ml。PCa与BPH两组间的前列腺体积及其移行区体积比较,差异无统计学意义（P〉0.05）;而PSAD与PSATZ则PCa组显著高于BPH组,差异有高度统计学意义（P〈0.01）。结论经直肠超声对PCa诊断的敏感性较高,特异性较低,结合PSAD及PSATZ则可提高对PCa的检出率。
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| 关 键 词： | 经直肠超声 前列腺癌 前列腺特异性抗原 |
The Diagnostic Value of Transrectal Ultrasonogrphy Combined with Prostate Specific Antigen Density in Prostate Cancer |
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| SHEN Wei-dong,ZHA Yue-qin,WANG A-jun,HOU Jian-quan,OUYANG Jun.The Diagnostic Value of Transrectal Ultrasonogrphy Combined with Prostate Specific Antigen Density in Prostate Cancer[J].Suzhou University Journal of Medical Science,2008,28(5). |
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| Authors: | SHEN Wei-dong ZHA Yue-qin WANG A-jun HOU Jian-quan OUYANG Jun |
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| Institution: | SHEN Wei-dong1,ZHA Yue-qin1,WANG A-jun1,HOU Jian-quan2,OUYANG Jun2 (1.Dept of Ultrasoundul,2.Dept of Urology,the First Hospital Affiliated to Soochow University,Jiangsu Suzhou 215006,China) |
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| Abstract: | Objective To discuss the value of transrectal ultrasound (TRUS) and prostate specific antigen density (PSAD) and prostate specific antigen density of transition zone (PSATZ) for diagnosing prostate cancer. Methods Chose cases of prostate cancer(PCa) and benign prostate hyperplasia(BPH) , each was 19,all the cases were authenticated by pathology .Then compared the characteristic of prostate cancer with prostate specific antigen(PSA) and homologous PSAD, PSATZ. Results Fourteen cases were discovered by ultras... |
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| Keywords: | transrectal ultrasound prostate cancer prostate specific antigen |
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