重症监护病房医院感染病原菌分布及耐药性分析

目的了解医院重症监护病房(ICU)医院感染病原菌分布及不同病原菌的耐药性,为临床合理选用抗菌药物提供依据。方法采用K-B法进行药敏试验,用双纸片协同法测定超广谱β-内酰胺酶(ESBLs)。结果共分离出128株菌,其中G-杆菌61株,占47.65%,真菌48株,占37.50%,G 球菌19株,占14.84%;产超广谱β-内酰胺酶大肠埃希菌为73.00%,肺炎克雷伯菌为55.13%。结论ICU患者免疫力低下极易感染病原菌或多种菌混合感染,且分离菌易呈多药耐药性,临床治疗较棘手,因此应在抗菌药物敏感试验指导下进行治疗。

Resistant Bacteria of Nosocomial Infection in ICU:Distribution and Surveillance

OBJECTIVE To investigate the distribution and resistance of bacteria of nosocomial infection in ICU.METHODS A total of 128 strains were detected by double-disc synergy test.RESULTS Among 128 strains from ICU,Gram-negative bacilli,accounted for 61 strains(47.65%),fungi for 48(37.5%),and Gram-positive cocci for 19(14.84%).Escherichia coli and Klebsiella pneumoniae were 73.00% and 55.13%.CONCLUSIONS The strains isolated from ICU are antibiotic-resistant.It is very impotant to select antibiotics correctly for infection of the patients in ICU according to the results of antibiotic susceptibility tests.