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Interim estimates of the effectiveness of influenza vaccination against influenza‐associated hospitalization in children in Hong Kong, 2015–16 |
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| Authors: | Joshua S. C. Wong Shuo Feng Chi‐Wai Leung Eunice L. Y. Chan Kwok‐Hung Chan Tak‐Keung Ng Wing‐Kin To Malik J. S. Peiris Susan S. Chiu |
| Affiliation: | 1. Department of Paediatrics and Adolescent Medicine, Princess Margaret Hospital, Hong Kong Special Administrative Region, China;2. WHO Collaborating Centre for Infectious Disease Epidemiology and Control, School of Public Health, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region, China;3. Department of Paediatrics and Adolescent Medicine, Queen Mary Hospital and Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region, China;4. Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region, China;5. Department of Pathology, Princess Margaret Hospital, Hong Kong Special Administrative Region, China;6. Department of Pathology, Yan Chai Hospital, Hong Kong Special Administrative Region, China;7. Center of Influenza Research, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region, China |
| Abstract: | From 1 September 2015 through 31 January 2016, we enrolled 2068 children 6 months to 17 years of age admitted to hospital with a febrile acute respiratory infection in our test‐negative study. Information on receipt of 2015–16 northern hemisphere inactivated influenza vaccination was elicited from parents or legal guardians. Using conditional logistic regression adjusting for age and matching on calendar time, we estimated influenza vaccine effectiveness against hospitalization with influenza A or B to be 79.2% (95% confidence interval: 42.0%–92.4%). Annual influenza vaccination should be more widely used in children in Hong Kong. |
| Keywords: | effectiveness hospitalization influenza interim pediatrics vaccine |