Incompatibility of water-soluble contrast media and intravascular pharmacologic agents. An in vitro study. |
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Authors: | S H Kim H K Lee M C Han |
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Institution: | Department of Diagnostic Radiology, Seoul National University College of Medicine, Republic of Korea. |
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Abstract: | In vitro incompatibilities between nine water-soluble contrast media and 21 intravascular pharmacologic agents were investigated using naked-eye observation and a centrifuge. Most of the previously reported incompatibilities were verified, and a few new incompatibilities were discovered: phentolamine mesylate with diatrizoate sodium, diatrizoate meglumine, ioxaglate, and iothalamate; diatrizoate meglumine with diazepam and meperidine hydrochloride; and diatrizoate sodium with meperidine hydrochloride. There were no incompatibilities when the pharmacologic agents investigated were mixed with ioxithalamate, iopromide, iopamidol, and iohexol. |
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