视黄醇结合蛋白研究与进展

本文对视黄醇结合蛋白的研究与进展进行了综述。ＲＢＰ为血液中转运视黄醇的蛋白,半衰期较短,能较为敏感地反映机体营养状况,特别是较短时间内蛋白质代谢的改变,可检测出早期和亚临床型营养不良。ＲＢＰ含量改变能较敏感地反映肾近端小管的功能,以及肝功能损害的程度,同时也是监测肾,肝及营养性疾病的发展和转归的敏感指标。

Study and advance of retinol-binding protein

The research and advance of the retinol binding protein(RBP) was reviewed in this article.RBP is thought to be responsible for the delivery of the serum retinol(Vtamin A) to target cell.Since the half life peried of RBP is much shorter,it can reveal the nutrition state of organs more sensitively,especially the change of the protein metablism in a short time.It can also checkout primary and subclinical malnutrition.On the other hand,the change of RBP can sensitively indicate the function of nephrotubular and the degree of the liver function injuried.Simultaneously it can serve as an index for detecting the development and the results of the diseases of kindey and liver,as well as nutritional diseases.