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吉米沙星治疗老年社区获得性肺炎疗效评价
引用本文:申先虎. 吉米沙星治疗老年社区获得性肺炎疗效评价[J]. 职业卫生与病伤, 2010, 25(1): 25-27
作者姓名:申先虎
作者单位:绵阳市中心医院呼吸内科,四川,绵阳,621000
摘    要:目的评价吉米沙星在社区获得性肺炎(CAP)老年人群中的疗效和安全性。方法采用前瞻性设计,将80例老年患者随机分为治疗组(42例)和对照组(38例),治疗组予吉米沙星片0.32 g,po,qd,疗程14 d。对照组予左氧氟沙星0.2 g,po,bid,疗程14 d。统计分析治愈率、症状缓解时间、不良反应等。结果疗程结束后,治疗组和对照组治愈率分别为91%和89%,差异无统计学意义(P0.05)。但在疗程早期治疗组治愈率高于对照组,差异有统计学意义(P0.05)。治疗组多种症状(发热、咳嗽、痰液性状改善、胸痛等)缓解时间更短,有统计学意义(P0.01,P0.05)。吉米沙星不良反应少,均可耐受。结论吉米沙星治疗老年CAP患者临床疗效肯定,安全,给药方便。

关 键 词:社区获得性肺炎  老年  临床对照试验  吉米沙星

Evaluation on Effect of Gemifloxacin in Treatment of Community Acquired Pneumonia in Elderly People
SHEN Xian-huThe Central Hospital of Mianyang Municipality,Mianyang ,Sichuan Province,China.. Evaluation on Effect of Gemifloxacin in Treatment of Community Acquired Pneumonia in Elderly People[J]. Journal of Occupational Health and Damage, 2010, 25(1): 25-27
Authors:SHEN Xian-huThe Central Hospital of Mianyang Municipality  Mianyang   Sichuan Province  China.
Affiliation:SHEN Xian-huThe Central Hospital of Mianyang Municipality,Mianyang 621000,Sichuan Province,China.
Abstract:Objective To evaluate the effect and safety of gemifloxacin for elderly patients with community acquired pneumonia(CAP).Methods By prospective design,80 elderly patients with CAP were randomly divided into trial group(42 cases) and control group(38 cases).Gemifloxacin(0.32g,po,qd) was administrated in trial group for 14 days,and levofloxacin(0.2g,po,bid) was given in control group for 14 days.The statistical difference was analyzed in terms of effect,side effect and compliance and the comparison was made be...
Keywords:Community acquired pneumonia  Elderly people  Controlled clinical trial  Gemifloxacin  
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