GA3, a new gambogic acid derivative,exhibits potent antitumor activities in vitro via apoptosis-involved mechanisms |
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Authors: | Hua XIE, Yu-xin QIN, Yun-long ZHOU, Lin-jiang TONG, Li-ping LIN, Mei-yu GENG, Wen-hu DUAN, Jian DING |
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Affiliation: | [1]Division of Antitumor Pharmacology ,State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China; [2]Department of MedicinaI Chemistry; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China |
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Abstract: | gambogic acid GA3 antitumor apoptosis caspase Bcl-2 cytochrome c |
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Keywords: | gambogic acid GA3 antitumor apoptosis caspase Bcl-2 cytochrome c |
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