Role of neuritic plaques and blood brain barrier in pathogenesis of Alzheimer''s disease
Authors:
Robert Katzman
Affiliation:
Department of Neurosciences, University of California at San Diego, La Jolla, CA, USA
Abstract:
The authors suggest primary roles for the neuritic plaque and a breakdown in the blood brain barrier in Alzheimer's disease. Although the role of the plaque seems reasonable and empirically justified, the hypothesized role for changes in the blood brain barrier remains in doubt.