Selenium deficiency in a patient with Crohn's disease receiving long-term total parenteral nutrition |
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Authors: | Ishida Tetsuya Himeno Katsuro Torigoe Yasuko Inoue Megumi Wakisaka Osamu Tabuki Takuo Ono Hidenobu Honda Koichi Mori Tetsu Seike Masataka Yoshimatsu Hironobu Sakata Toshiie |
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Affiliation: | Department of Internal Medicine I, School of Medicine, Oita Medical University, Oita. |
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Abstract: | We report a case of selenium deficiency in a patient with Crohn's disease on long-term total parenteral nutrition (TPN). She manifested lassitude of the legs, discoloration of the nail beds, and macrocytosis. Since her plasma selenium level was found to be below the measurable level, we diagnosed this case as selenium deficiency. After intravenous administration of sodium selenite, her symptoms were reversed. Careful attention should be paid to selenium deficiency when a patient receives long-term TPN; supplementary administration of selenium via TPN may be required because selenium is often not routinely added to TPN formulations. |
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