动态动脉硬度指数与脉搏波速度的相关性研究

目的 研究动态动脉硬度指数(AASI)与脉搏波速度(PWV)的相关性,探讨AASI对动脉硬化程度的评价价值,并分析AASI的影响因素.方法 人选患者100例,进行臂-踝PWV测量,并同时进行24h动态血压监测(ABPM),计算AASI.应用直线相关分析判定AASI与PWV的相关性.并应用多因素逐步回归分析判定AASI的影响因素.结果 AASI与PWV和年龄显著正相关(PWV:r＝0.516,P＜0.01;年龄:r＝0.417,P＜0.01).AASI与身高呈负相关r＝-0.223,P＜0.05).多因素逐步分析结果表明,PWV是与AASI关系最密切的参数.结论 AASI与PWV相关性良好,是一个反映动脉硬化程度的新指数.

Study on correlation of ambulatory arterial stiffness index and pulse wave velocity

Mective To study the correlation of ambulatory arterial stiffness index(AASI)and pule wave velocity(PWV),explore the evaluation of AASI on arterial stiffness and analyze the influential factors of AASI.Method One hundred patients were selected,brachial-ankle pulse wave velocity (baPWV)of all patients wag measured,simultaneously 24-hour ambulatory blood pressure Wag examined, calculated AASI.AASI and baPWV were analyzed with correlation and regression analysis.Results AASI Wagpositively and signifieandy correlatedwithPWV(r＝0.516,P＜0.01)and age(r＝0.417,P＜0.01). AASIWag negatively correlatedwithbody height(r＝-0.223,P＜0.05).Themultiplefactor stepwise regres-sion analysis showed that the regression of AASl with PWV were great significant.Conclusions AASI is positively and significantly correlated with PWV.It is a novel meagure ofartdrial stiffness.