Effects of inducible nitric oxide synthase inhibition or norepinephrine on the neurovascular coupling in an endotoxic rat shock model期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

Effects of inducible nitric oxide synthase inhibition or norepinephrine on the neurovascular coupling in an endotoxic rat shock model

Authors:	Bernhard Rosengarten Stephanie Wolff Sabine Klatt Ralf T Schermuly

Affiliation:	(1) Department of Neurology, Justus Liebig University Giessen, Am Steg 14, Giessen, 35392, Germany;(2) Department of Internal Medicine II, Justus Liebig University Giessen, Klinikstrasse 36, 35392 Giessen, Germany

Abstract:	Introduction The inducible nitric oxide synthase (iNOS) plays a crucial role in early sepsis-related microcirculatory dysfunction. Compared to a catecholamine therapy we tested effects of a specific iNOS-inhibitor (1400W) on the microcirculatory function in the brain.

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